Inclusion: Rotterdam criteriaExclusion: History of any underlying and chronic disease (chronic kidney disease, etc.), history of abdominal and pelvic surgery, abnormal hysterosalpingography, abnormal serum prolactin level, smoking, pregnancy, current or previous Statin use during the past 2 months, insulin use, use of corticosteroids, anti-obesity medication, and history of neoplastic diseases. This evidence concerns the gene INS and neoplasm.