All six thermogenes appear to be significantly overexpressed in breast cancer (HSPA1A, HSPA4), gliomas (DNAJB5), ovarian cancers (HSPA4, DNAJB5), pancreatic cancers (HSP90AA1), prostate cancer (HSP90AB1), thymic carcinoma (BAG1, HSP90AA1), and uterine cancers (HSPA4), as compared to normal tissue (Figure 3). Here, HSP90AA1 is linked to central nervous system cancer.