HSP90AB1 and central nervous system cancer: All six thermogenes appear to be significantly overexpressed in breast cancer (HSPA1A, HSPA4), gliomas (DNAJB5), ovarian cancers (HSPA4, DNAJB5), pancreatic cancers (HSP90AA1), prostate cancer (HSP90AB1), thymic carcinoma (BAG1, HSP90AA1), and uterine cancers (HSPA4), as compared to normal tissue (Figure 3).