SLC7A11 and cancer: As cancer cells in this state are strongly susceptible to glutathione depletion [85], and cysteine/glutamate antiporter xCT controls glutathione synthesis and Nrf2 contributes to respiratory re-activation, Ždralević et al. proposed a mechanism of cancer cell death called “ferroptosis” as a new target for cancer therapy, i.e., an inhibition of xCT antiporter; this allows for the use of the acute lethal peroxidation of phospholipid to cause the death of aggressive cancer cells [81].