ANXA1 and osteoporosis: For annexin A1 mRNA, the strongly significant decline was evident between nonosteoporotic and osteopenia groups (Figure 1(a) and Table 2; nonosteoporotic control group vs. osteopenia, 95% CI 0.208 to 0.476, P < 0.0001; nonosteoporotic control group vs. osteoporosis, 95% CI 0.262 to 0.566, P < 0.0001; osteoporosis vs. osteopenia, 95% CI -0.192 to 0.049, P = 0.242, post hoc Bonferroni correction).