ROC curve analysis for nonosteoporotic controls and osteoporosis showed that, when all participants were included, the areas under the ROC curves for annexin A1, TMEM64, and S100A4 were 0.893, (Figure 3(a), 95% CI 0.796 to 0.99; sensitivity 0.882, specificity 0.783), 0.742 (Figure 3(b), 95% CI 0.577 to 0.907; sensitivity 0.813, specificity 0.696), and 0.783 (Figure 3(c), 95% CI 0.637 to 0.929; sensitivity 0.882, specificity 0.652), respectively. This evidence concerns the gene TMEM64 and osteoporosis.