The genes EPHB1, KIAA1614, SACS, SMAD4, PCDHA1, TNS1, CACNA1C, DEPDC1, PCDHGA9, LRP4, KLHL2, CDC20, ARHGEF39, CGNL1, SKIV2L2, FAM196A, IL6ST, ATP2B4, TGFBR3, TIGD3, NOS1, SRSF2, MYO9A, KIF13A, UBR3, WIF1, LRGUK, ERBB4, and NYNRIN had mutations in aggressive PCa only (Table 1). Here, CACNA1C is linked to posterior cortical atrophy.