Through the PANTHER classification system pathway analysis, it was found that 74 pathway-related genes were involved in a total of 39 primarily signaling pathways, among which the pathways with higher frequency were Wnt signaling pathway (P00057), angiogenesis (P00005), P53 pathway (P00059), Alzheimer disease-presenilin pathway (P00004), notch signaling pathway (P00045), and cadherin signaling pathway (P00012). This evidence concerns the gene TP53 and early-onset autosomal dominant Alzheimer disease.