BRCA2 and breast cancer: General risk factors that increase the chance of developing breast cancer may include: family history of the disease in immediate female family members; personal history of benign breast tumor; personal history of invasive, in situ or lobular malignancy; dense mammary tissue; inherited genetic mutations of breast cancer genes (e.g., BRCA1, BRCA2); early onset of menarche; older age of first birth; exposure to radiation; obesity; alcohol consumption; sedentary lifestyle; hormonal treatment of menopause [8], and high fat consumption [9].