The genetic variability of the telomerase reverse transcriptase (TERT) could play a role in MM etiology as this gene is responsible for telomere homeostasis and their polymorphic variants have been incriminated in several human cancers.12, 20, 21 Few studies were done concerning the impact of telomere length and genetic polymorphic pattern association as risk factor in those patients. This evidence concerns the gene TERT and Miyoshi myopathy.