Indeed, p75NTR via Tumor necrosis factor receptor type 1-associated DEATH domain-dependent (TRADD-dependent), NF-kB and Brain expressed X-linked (BEX) drives a prosurvival effect in breast cancer and schwannoma, while being anti-cancerogenic via JNK-mediated apoptosis in prostate cancer cells and neurons [72–74]. This evidence concerns the gene NFKB1 and breast cancer.