AFP and hepatocellular carcinoma: Although various proteins biomarkers such AFP, CEA, miRNA or lncRNAs have been isolated from exosomes as potential fingerprint for different approach, little is known about plasma exosome‐derived lncRNAs in HCC, little systematic study was conducted by using the high throughput detection of lncRNA, also many lncRNAs in exosomes have not been adequately investigated.