The level of MFGE8 protein was increased significantly in SLE patients with rs4945 CA or AA genotype than in SLE patients with rs4945 CC genotype (5,136.1 ± 2,140.5 pg/mL vs. 1841.8 ± 1,168.6 pg/mL, P < 0.001; Table 4). This evidence concerns the gene MFGE8 and systemic lupus erythematosus.