Using an identical protocol to the original DSS-induced colitis experiment (Fig. 6), we ran a smaller experiment with mice randomly assigned to one of three experimental groups: colitic group (PBS DSS+), DSS treated soluble TFF3 group (PBP8 N22-TFF3 DSS+) and DSS treated curli-bound TFF3 group (PBP8 CsgA-TFF3 DSS+). Here, TFF3 is linked to colitis.