HLA-A and influenza: However, as the remaining 65% of HLA-A*68:01-expressing donors had low precursor frequency of A68/NP145+CD8+ T cells, which indicates possible difficulties with the recruitment of A68/NP145+CD8+ TCRαβ clonotypes during influenza-specific responses, as compared with the engagement of TCRαβ clones against universal influenza CD8+ T cell epitopes in the same donors.