To understand whether low detection of A68/NP145+CD8+ T cell populations found in 65% of our donors resulted from the establishment of differential naïve/memory subsets within the A68/NP145+ CD8+ T cells, we compared directly ex vivo the phenotypes of A68/NP145+CD8+ T cells both (i) across HLA-A*68:01-expressing donors, and (ii) with phenotypes of CD8+ T cells directed at universal influenza epitopes (Fig. 4). This evidence concerns the gene HLA-A and influenza.