Liver metastasis from colon cancer was associated with a higher intratumoural CD8/CD3 ratio (73.5% vs. 52.3%, p = 0.011), peritumoural CD8/CD3 ratio (72.6% vs. 54.9%, p = 0.035), and peritumoural Foxp3/CD3 ratio (77.8% vs. 55.8%, p = 0.013) than rectal cancer. The gene discussed is CD8A; the disease is malignant colon neoplasm.