ERLIN1 and viral infectious disease: Importantly, our results identify erlin-1 protein as a new positive modulator of HCV infection and together with the results described by Inoue et al. in the SV40 infection system [28] point to the need of investigating the role of erlin proteins in other viral infections, especially in those in which their life cycle is tightly associated with the ER e.g., dengue virus or zika virus infection.