TAMs are recruited to the tumour site by CCL2, CCL5, VEGF, and CSF1 and participate in a variety of pro-tumourigenic processes, such as angiogenesis (VEGF), cell proliferation (EGF) and epithelial-mesenchymal transition, tumour metastasis, immunosuppression (IL-10 and TGF-β), ECM remodelling (MMPs), and reduction of anticancer therapies efficacy [122]. Here, CCL2 is linked to neoplasm.