MKI67 and neoplasm: We further conducted histopathology assays of the excised tumor from each group, including hematoxylin and eosin (H&E) staining (Figure 3) and immunohistochemistry staining (IHC) in response to tumor suppressor protein p53 of total protein (TP53), tumor cell proliferation (Ki-67), tumor microvessel (CD31), and tumor cell apoptosis (cleaved caspase-3, TUNEL) (Figure 4).