IL5 and infection: In additional, epithelial alarmins are secreted following infection with parasitic nematodes to activate type 2 innate lymphoid cells (ILC2) and drive type 2 immunity [37,44,45], which via IL-5 and IL-13 can mobilize wound healing mechanisms with the capacity to produce Arg1 [44] and FIZZ1 [46] to maintain tissue integrity.