IL22 and type 2 diabetes mellitus: One month after T2DM induction, the mice were aerosol infected with ~100 CFU of Mtb, and at five months p.i., the mice were intravenously treated with a single dose or a twice weekly regimen (up to 35 weeks), of recombinant IL-22 (100 ng/kg body weight) or PBS as described in the methods section.