PDGFA and chondrosarcoma: Evaluation of S1P-regulated angiogenesis in chondrosarcoma cells by EPC migration and tube formation assays [27] revealed that conditioned medium (CM) from S1P-treated chondrosarcoma cells stimulated EPC migration and tube formation (Figure 1C, 1D), whereas PDGF-A monoclonal antibody (mAb) treatment suppressed these events (Figure 1C, 1D).