PLCD3 and neoplasm: After adjusting for OS‐related clinical variables, which included targeted molecular therapy, radiation therapy, residual resection, and neoplasm histological grade, the results of Cox proportional hazard regression elucidated that PLCD3 is significantly related to overall survival for the 112 PDAC patients (P = .020; adjusted P = .016) (Table 1, Figure 3B).