Recently, the correlation between CT signs of lung adenocarcinoma and common gene mutations of EGFR and ALK has been studied.7, 8, 9, 10, 11, 12, 13, 14 It has been reported that EGFR mutation is correlated with CT signs, such as ground‐glass density, burr, air bronchus sign, and ALK mutation is more common in the lobular margin. This evidence concerns the gene EGFR and lung adenocarcinoma.