Thirty hours after the admission, laboratory examination demonstrated leukocytosis at 18,000/μl, 93.5% neutrophils, C-reactive protein of 13.7 mg/dl, fibrin/fibrinogen degradation products at 12.2 μg/ml (normal range, 0.0–5.0 μg/ml), D-dimer levels of 4.7 μg/ml (normal range, 0.0–1.0 μg/ml), base excesses of − 4.5 mmol/l (normal range, − 2.5–2.5 mmol/l), and nearly normal hemoglobin, electrolytes, creatinine, AST, and amylase. The gene discussed is CRP; the disease is Increased total leukocyte count.