Strikingly, tactile deficits caused by Cre-lox mediated developmental deletion of Mecp2, Gabrb3, or Shank3 specifically in DRG neurons led to behavioral deficits resembling some of the core phenotypes of ASD (anxiety-like behaviors, reduced sociability, and reduced preferences for social novelty) [98, 99]. The gene discussed is GABRB3; the disease is Anxiety.