The answer is, unfortunately, no. Liu et al. [74] showed that S1PR1 can accelerate VE-cadherin phosphorylation (Y731) by activating RhoA, leading to increased endothelium-dependent vessel and reduced vasculogenic mimicry in breast cancer, and the low expression of S1PR1 is in line with the vasculogenic mimicry and poor prognosis in breast cancer patients. The gene discussed is RHOA; the disease is breast cancer.