Our differential and functional gene analysis in stathmin-modulated cells has identified a subset of candidate targets with predicted functions in cell migration and adhesion such as PTPN14,18 PVRL3,29 ADAM1230 and VEGFC.31 These results converged into a global modulation of cell–cell and cell–matrix interactions having essential roles in cell motility and migration, confirming that stathmin expression can modulate aggressive, metastatic neuroblastoma in part by regulation of genes with functions in cell migration and adhesion. The gene discussed is NECTIN3; the disease is neuroblastoma.