YBX1 and central nervous system cancer: For example, downregulation of GOLPH3 by RNA interference inhibited glioma cell migration and invasion via the mTOR-YB1 pathway.23 Recently, Dai et al found that GOLPH3 overexpression alleviated cisplatin-induced HCC cell apoptosis, and promoted the aggressiveness of HCC cells via NF-κB pathway.16 In the present study, GLOPH3 was confirmed to be a target of miR-3150b.