AFP and hepatocellular carcinoma: Serum AFP (p<0.001), HBsAg (p = 0.01), AST (p = 0.046), IBIL (p<0.001) and ALB (p = 0.049) were significantly predictive of HCC after multivariate logistic regression analysis in the training data set and were incorporated with the Rad-score to formulate a radiomics-clinical nomogram (Fig. 3c).