Because omentin levels are known to be inversely correlated to parameters of obesity and the metabolic syndrome [4, 13, 36, 37], plasma omentin levels could be elevated in association with lower BMI, lower insulin resistance index, and higher HDL-cholesterol levels in high-adiponectin group of our T2D patients. This evidence concerns the gene ADIPOQ and obesity due to melanocortin 4 receptor deficiency.