PVALB and early-onset autosomal dominant Alzheimer disease: The hypersynchrony reported in the cortical and hippocampal electroencephalogram (EEG) recordings of hAPPJ20 mouse used as an Alzheimer’s disease mouse model [141] was associated with the reduction of gamma oscillation [142], which depends on the synaptic activity of the fast-spiking parvalbumin-GABAergic neurons [143,144].