Some of these changes were in line with RNAseq data, such as ERBB2/HER2 which was massively upregulated in both, the KRASWT tumor proteome (also compared to all of our reference proteomes) and transcriptome as a consequence of a gene amplification (region chr17:37, 690, 344-40,762,015). Here, ERBB2 is linked to neoplasm.