KRT19 and hepatocellular carcinoma: The evolution of preneoplastic lesions has been characterized as showing a positivity for the hepatocyte progenitor cell marker, cytokeratin-19 (CK19), in 25% of preneoplastic nodules, in 50% of persistent lesions, and in all HCCs, demonstrating that CK19-positive preneoplastic lesions are more likely the progenitor of HCC in this model.