AFP and hepatocellular carcinoma: Subsequently, we found that LSD1 protein expression in HCC patients was significantly associated with female gender (p = 0.018, Fisher’s exact test), non-alcoholic abuse history (p = 0.0027), HCV (hepatitis C virus) infectious (p = 0.038), no infectious history (p = 0.013), AFP (alpha-fetoprotein) levels (p < 0.001), CA 19–9 levels (p = 0.017), hepatic vein invasion (p = 0.017) and fibrosis stage F4 (p = 0.0061).