As shown in Table 3, IBP could not inhibit the infection by any HIV-1 clinical strains or pseudoviruses at concentration as high as 1,000 nM, while IBP-CP24 could effectively inhibit infection by 8 HIV-1 clinical strains tested in a dose-dependent manner with an average IC50 of 32.3 nM, about 2.5- and 1.1-fold of that of T20 and CP24, respectively. Here, CYP24A1 is linked to infection.