MED23 and Hepatic fibrosis: Considering the connection between liver metabolism and chronic liver diseases, we sought to determine whether MED23 might be involved in the pathogenesis of liver fibrosis, and we found that the silencing of Med23 in hepatocytes aggravates the development of carbon tetrachloride (CCl4)-induced hepatic inflammation and fibrosis, thus defining an important role of hepatic MED23 in liver fibrosis.