To investigate the role of MED23 in liver fibrosis, we employed the well-established CCl4-induced mouse model of liver fibrosis [25], in which the control med23-floxed (med23f/f) mice and mice with hepatocyte-specific Med23 deletion (med23Δli) [18] were intraperitoneally injected with CCl4 every 3 days for 1 month. Here, MED23 is linked to Hepatic fibrosis.