Similar to the CCl4-induced fibrosis model, Med23 silencing also resulted in increasing mRNAs related to liver fibrosis, including Col1a1, Col3a1, Tgfβ1, Pdgfβ, Tgfβr1, Pdgfrβ, and Timp1 (S1A Fig). This evidence concerns the gene TGFB1 and Hepatic fibrosis.