In a study by Chu et al. [27], inhibition of CASP12 expression causes an increase in the invasiveness of nasopharyngeal carcinoma cells, and in a study by Cheng et al. [28], overexpression of CASP12 inhibits the proliferation of hepatoma HEP-J5 cells. The gene discussed is CASP12; the disease is hepatocellular carcinoma.