Furthermore, the association between a SNP in the 9p21 region and incident CHD was replicated in Asian/Pacific ethnicity later, but no significant association between 1q419 (rs17465637, MIA3) or 10q11.21 (rs501120, CXCL12) and CHD was observed in the Asian population in this replication study23. The gene discussed is MIA3; the disease is coronary artery disorder.