Immunohistochemistry (IHC) markers are useful in differentiating MNTI from various other small cell tumors of infancy, such as embryonal rhabdomyosarcoma, Burkitt lymphoma, neuroblast, malignant neuroectodermal tumors.[7] IHC showed that the large epithelioid/melanocytic cells were positive for cytokeratin (CK), vimentin and HMB-45, and partly for S-100, while the small neuroblast-like cells were positive for S-100, NSE and CD56. The gene discussed is ENO2; the disease is embryonal rhabdomyosarcoma.