From the results above, we can see different degrees of protection by the four different components of FMT on the DSS-induced colitis, through improving the intestinal barrier integrity, reducing the cytokines and immune cells in colon and inhibiting the TLR4-MyD88-TRAF6-NF-κB signaling, accompanied by the remarkable reduction in digestive proteases trypsin and chymotrypsin and increase in β-glucuronidase. The gene discussed is NFKB1; the disease is colitis.