HLA-DRB1 and infection: We continue to see up-regulated genes that are likely part of a continued immune response to infection, including two MTs (MT1M and MT1E), TRIM25 (Tripartite Motif Containing 25), ISG15 (ISG15 Ubiquitin Like Modifier), HLA-A (Major Histocompatibility Complex, Class II, DR Beta 1), IFIT3 (Interferon Induced Protein With Tetratricopeptide Repeats 3), OASL (2′-5′-Oligoadenylate Synthetase Like), IL6 (Interleukin 6), and genes associated with cholesterol and fatty acid synthesis (Figure 6B).