Moreover, hsa_circ_0007841 expression was also detected in THP-1 mononuclear cells, MM cell lines (KM3, U266, 8226), drug-resistant cell lines (KM3/BTZ, U266/BTZ, 8226/BTZ) (Figure 2E) and patients with MM with BTZ resistance (Figure 2D). The gene discussed is CASC3; the disease is Miyoshi myopathy.