We had thus far observed that miR-184 induced apoptosis and G2/M phase arrest of RB cells in response to chemotherapy, to further unveil the detailed molecular mechanisms, we therefore used multiple bioinformatics algorithms (TargetScan, Starbase, and miRTarBase) and found that TNPO2 and SLC7A5 are two predicted targets of miR-184 (Figure 4A). The gene discussed is TNPO2; the disease is retinoblastoma.