The metabolic phenotype observed for Cav1Y14D tumor cells is consistent with TP53-associated reversal of the Warburg type-effect, reducing glucose uptake into glycolysis, hexosamine biosynthesis pathway (HBP) and nucleotide biosynthesis, while promoting carbon flux to oxidative respiration, DNA damage repair and resistance to oxidative stress [33]. Here, TP53 is linked to neoplasm.