PPARA and familial dilated cardiomyopathy: Pathway analysis of NONHSAT001691 and NONHSAT006358 showed that the metabolic pathways were mainly enriched, including the AMPK, PPAR, adipocytokine, glucagon, and fatty acid degradation signaling pathways, all of which have been shown to play important roles in DCM (Nikolaidis et al., 2004; Giannessi et al., 2011; Roh et al., 2014; Sung et al., 2015).