Notably, the inability of NK cell to produce IL-10 did not influence the viral burden in MCMV-infected PKO mice, as PKO-NKp46-Cre-Il10fl/fl had similar virus titer in their spleens and livers as compared with their control littermates PKO-Il10fl/fl at D5 post-infection (Figure 6D). This evidence concerns the gene IL10 and infection.