IL1R1 and cystic fibrosis: In CF patients, miR-636 and RANK appeared to be non-significantly overexpressed (Figures 2A,C); IL1R1 mRNA levels were significantly lower (Figure 2B); IKBKB, FAM13A, and IL-8 mRNA levels were significantly higher (Figures 2D–F), while IL-6 mRNA seemed to be decreased (Figure 2G) compared to non-CF controls.