MiR-10a is upregulated in the differentiated NB cell lineage after administration of all-trans-retinoic acid (ATRA) (53), and one mechanism may be miR-10b inhibition of Nuclear Receptor Corepressor 2 (NCOR2), a transcriptional co-repressor, which regulates the genes involved in differentiation of NB cells (54). The gene discussed is NCOR2; the disease is neuroblastoma.