RETN and Insulin resistance: Several studies found positive correlations between resistin and insulin resistance in T2DM, obese and healthy individuals (Al-Harithy and Al-Ghamdi, 2005; Hivert et al., 2008; Zaidi and Shirwany, 2015); this discovery appears to be supported by studies reporting significantly higher resistin levels in populations with T2DM (Heilbronn et al., 2004).