Long noncoding RNA nuclear paraspeckle assembly transcript 1 (LncRNA NEAT1), a nuclear‐restricted long noncoding RNA, modulates gene expression in nucleus and consequently regulates pathophysiological processes.19, 20 LncRNA NEAT1 promoted the proliferation and progression of human breast cancer in hypoxia.21 Moreover, lncRNA NEAT1 effectively inhibited the degradation of PINK1 protein and strongly suppressed MPTP‐induced autophagy in Parkinson's disease.22 However, whether NEAT1 could regulate the autophagy in CRC needs to be highly developed. This evidence concerns the gene NEAT1 and breast cancer.