It was also demonstrated that autophagy modulated chemoresistance of glioblastoma through balance of mitochondrial bioenergetics,26 which indicated the important role of autophagy in chemoresistance; NEAT1 bound with PINK1 protein and promoted the autophagy in MPTP‐induced Parkinson's disease.22 Silence of NEAT1 showed a protective effect on MPTP‐induced Parkinson's mice.27 However, whether NEAT1 regulated autophagy in cancer was elusive. This evidence concerns the gene NEAT1 and Parkinson disease.