Both J82/Control and J82/GABPA cells formed metastatic nodules in mouse livers but rarely in lungs; However, the number of tumor colonies were substantially fewer in livers from mice harboring J82/GABPA cells (J82/Control vs J82/GABPA: 15 ± 5/liver vs 3 ± 1/liver, P = 0.041) (Fig. 5a, b). This evidence concerns the gene GABPA and neoplasm.